Patients with sepsis and previous seizures usually were older, with a greater amount of total body surface burned and a longer latency to the seizures than patients with other types of etiology. The other etiologies encountered include hypoxia, hemoconcentration, hemodilution, acidosis, hypertension, sepsis, hexachlorophene and previous history of seizure disorder. The one single factor that seems most significant is hyponatremia, in association with cellular hydration and even cerebral edema. The etiology of these seizures is varied, just as in all other forms of epilepsy. Patients with seizures have a significantly higher percentage of total body surface burned than most patients admitted to a burn unit. Young infants have attacks usually with a shorter latency than older children.
Beyond that time the latency varied considerably, but most cases of seizures occurred within 2 mth after the burn. The latency to seizures was highest at 18 to 24 hr after the burn, then linearly fell to the fifth day. Seizures were usually generalized, at times with a unilateral predominance, more often right sided, appearing in patients usually under the age of 12 yr with the highest incidence in the second year of life. In this collaborative study the effects of burns on the CNS have been studied, especially seizures (73 cases) and cognitive or behavior disorders (217 cases).
#After burn skin
Seizures may occur in patients with burns of the skin and the term 'postignitic epilepsy' is proposed for this condition.
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